This window will soon give access to POLYS, the molecular builder for generating three-dimensional structures of polysaccharides and complex carbohydrates. Using this software, complex branched carbodydrate containing structures can be easily built from a primary structure and the relevant monosaccharide stored in data base containing information on glycoside linkage sub optimized disaccharide segments. The POLYS program is written in portable ANSI C, which can be compiled on most commonly available computing platforms in use today, making it easily accessible for both users and developers with the aim of improving its efficiency. User accessibility is ensured by simple ASCI based syntax for translating the (macro-) molecular primary structures following closely the IUPAC Nomenclature, into POLYS commands or scripts. These are then run through a command interpreter that is able to construct three dimensional structures described as Cartesian coordinate files which can be further used as input to other software such as molecular mechanics or quantum chemistry packages. The new version of POLYS is now released under an open source license, making it freely available to the public and offering opportunities to participate in the project development. The main website for POLYS is and the main code repository is at

POLYS – An Open Source Software Package for Building Three Dimensional Structures of Polysaccharides, by Peter I. Hansen , Serge Pérez & Soeren B. Engelsen, Quality & Technology, Department of Food Science, University of Copenhagen, Rolighedsvey 30, DK-1958 Frederiksberg C. Copenhagen, Denmark and Centre de Recherches sur les Macromolécules Végétales, CNRS, BP 53X, 380451 Grenoble Cedex France


How to cite this work : S. Pérez, A. Sarkar, A. Rivet, C. Breton & A. Imberty (2015) Glyco3D : A portal for structural glycosciences. Meth. Mol. Biol. 1273, 241-258